Unparalleled in identifying the presence and populations of various cells in blood and bone marrow, flow cytometry is based on the principle of a stream of single cells passing before a set of lasers that discreetly detect, sort, and count them.
Antibodies (markers) attached to proteins expressed by the cells then allow hematopathologists to see population patterns associated with malignancy or disruption of cell cycles and regulation.
Flow Cytometry Add-On Panels |
Markers |
---|---|
AML Add-On Panel | cCD3, cCD13, CD13, CD19, cCD22, CD33, CD34, CD41, CD45, CD61, cCD79a, cMPO, nTdT |
B-ALL Add-On Panel | CD10, CD19, CD20, CD22, CD33, CD34, CD38, CD45, CD58, CD123, cIgM |
CLL Prognostication Add-On Panel | CD5, CD19, CD45, CD49d, CD52, CD56, ZAP-70 |
Follicular / Large B-Cell Lymphoma Add-On Panel | BCL2, CD10, CD19, CD45 |
Hairy Cell Leukemia Add-On Panel | CD11c, CD19, CD25, CD45, CD103, CD123 |
Limited Myeloid Screen Panel | CD13, CD14, CD16, CD19, CD33, CD34, CD45, CD117, HLA-DR |
Mast Cell Panel | CD2, CD25, CD45, CD117 |
T-ALL Add On Panel | CD1a, CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD34, CD45 |
Flow Cytometry Panels | Markers |
---|---|
AML Panel | CD2, CD3, CD4, CD7, CD8, CD10, CD11b, CD13, CD14, CD15, CD16, CD19, CD33, CD34, CD36, CD38, CD45, CD56, CD64, CD65, CD71, CD105, CD117, CD123, CD235a, HLA-DR, Kappa, Lambda, nTdT, cMPO, cCD3, cCD13, cCD22, cCD79a, CD41, CD61 |
Lymphocyte Subset Panel | CD3, CD4, CD8, CD19, CD45, CD56 |
Lymphoplasmacytic Lymphoma Panel (LPL) | CD3, CD4, CD5, CD8, CD10, CD19, CD20, CD23, CD27, CD28, CD38, CD45, CD56, CD79b, CD81, CD117, CD138, IgA, IgG, IgM, surface Kappa, surface Lambda, cytoplasmic Kappa, cytoplasmic Lambda |
Lymphoproliferative Disorders Panel (LPD) | CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD16, CD19, CD20, CD23, CD38, CD43, CD45, CD56, CD57, CD79b, CD103, CD123, CD200, Kappa, Lambda |
Myelodysplastic Syndrome Panel (MDS) | CD2, CD3, CD4, CD7, CD8, CD10, CD11b, CD13, CD14, CD15, CD16, CD19, CD33, CD34, CD36, CD38, CD45, CD56, CD64, CD65, CD71, CD105, CD117, CD123, CD235a, HLA-DR, Kappa, Lambda |
Myeloproliferative Disorders Panel (MPD) | CD3, CD4, CD5, CD8, CD14, CD19, CD20, CD33, CD34, CD38, CD45, CD56, Kappa, Lambda |
Myeloma Panel | CD3, CD4, CD8, CD19, CD20, CD27, CD28, CD38, CD45, CD56, CD81, CD117, CD138, IgA, IgG, IgM, cKappa, cLambda |
Pancytopenia Panel | CD2, CD3, CD4, CD5, CD7, CD8, CD14, CD16, CD19, CD20, CD33, CD34, CD38, CD45, CD56, CD57, CD103, CD123, Kappa, Lambda, TCR gamma/delta |
Paroxysomal Nocturnal Hemoglobinuria Panel (PNH) "High sensitivity PNH Panel" (Meets International Clinical Cytometry Society guidelines) |
CD14, CD15, CD24, CD33, CD45, CD59, CD235a, FLAER |
T/NK-Cell Lymphoma Panel | CD2, CD3, CD4, CD5, CD7, CD8, CD16, CD19, CD38, CD45, CD56, CD57, Kappa, Lambda, TCR gamma/delta |
Desiree A. Carlson, MD
Chief of Pathology, Signature Healthcare
With core values rooted in service and integrity, our leadership team sets the bar high.
We consistently strive to set the model for exactly how a reference laboratory should engage with both physicians and patients.
siParadigm is accredited by CLIA (Clinical Laboratory Improvement Amendments) and certified by CAP (College of American Pathologists).
We also hold select state licensure where required.